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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERBB3
All Species:
26.36
Human Site:
S869
Identified Species:
52.73
UniProt:
P21860
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21860
NP_001005915.1
1342
148098
S869
D
D
K
Q
L
L
Y
S
E
A
K
T
P
I
K
Chimpanzee
Pan troglodytes
XP_509131
1342
148124
S869
D
D
K
Q
L
L
Y
S
E
A
K
T
P
I
K
Rhesus Macaque
Macaca mulatta
XP_001113953
1342
148045
S869
D
D
K
Q
L
L
Y
S
E
A
K
T
P
I
K
Dog
Lupus familis
XP_538226
1536
167696
S1066
D
D
K
Q
L
L
H
S
E
A
K
T
P
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61526
1339
147594
S867
D
D
K
Q
L
L
H
S
E
A
K
T
P
I
K
Rat
Rattus norvegicus
Q62799
1339
147527
S867
D
D
K
Q
L
L
H
S
E
A
K
T
P
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508590
1260
141049
G815
W
C
V
Q
I
A
K
G
M
M
Y
L
E
E
R
Chicken
Gallus gallus
P13387
703
77409
C258
R
E
S
D
C
L
A
C
R
K
F
R
D
D
A
Frog
Xenopus laevis
NP_001089061
1299
145796
R849
E
E
R
R
L
V
H
R
D
L
A
A
R
N
V
Zebra Danio
Brachydanio rerio
NP_001122291
1429
159077
S870
D
D
K
K
Y
V
Y
S
E
H
K
T
S
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P04412
1426
159700
K954
G
A
F
G
R
V
Y
K
G
V
W
V
P
E
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P24348
1323
150493
A866
P
E
L
T
P
I
D
A
S
V
R
P
N
M
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.7
81.1
N.A.
90.6
90.4
N.A.
48.3
25.9
47
48.4
N.A.
24.9
N.A.
21.1
N.A.
Protein Similarity:
100
99.9
99.2
83.1
N.A.
94.2
94.5
N.A.
63.9
35.2
63.3
61.6
N.A.
39.8
N.A.
38.5
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
6.6
6.6
6.6
66.6
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
13.3
53.3
80
N.A.
20
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
9
9
0
50
9
9
0
0
9
% A
% Cys:
0
9
0
0
9
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
59
59
0
9
0
0
9
0
9
0
0
0
9
9
0
% D
% Glu:
9
25
0
0
0
0
0
0
59
0
0
0
9
17
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
9
0
0
9
0
0
0
9
9
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
34
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
9
0
0
0
0
0
0
0
59
0
% I
% Lys:
0
0
59
9
0
0
9
9
0
9
59
0
0
0
59
% K
% Leu:
0
0
9
0
59
59
0
0
0
9
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
9
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% N
% Pro:
9
0
0
0
9
0
0
0
0
0
0
9
59
0
0
% P
% Gln:
0
0
0
59
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
9
9
9
0
0
9
9
0
9
9
9
0
9
% R
% Ser:
0
0
9
0
0
0
0
59
9
0
0
0
9
0
9
% S
% Thr:
0
0
0
9
0
0
0
0
0
0
0
59
0
0
0
% T
% Val:
0
0
9
0
0
25
0
0
0
17
0
9
0
0
9
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
42
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _